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NURS6501 Pathophysiology Week 7 With Answers (21 Solved Questions)

NURS6501 Pathophysiology Week 7 With Answers provides an insight into real exam scenarios with past test papers.

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Question 1:A 28-year-old woman presents to the clinic with a chief complaint of hirsutism and irregularmenses. She describes irregular and infrequent menses (five or six per year) since menarcheat 12 years of age. She began to develop dark, coarse facial hair when she was14 years of age, but her parents did not seek treatment or medical opinion at that time. Thesymptoms worsened after she gained weight in college. She got married 3 years ago andhas been trying to get pregnant for the last 2 years without success. Height 66 inches andweight 198. BMI 32 kg.m2. Moderate hirsutism without virilization noted.Laboratory datareveal CMP within normal limits (WNL), CBC with manual differential (WNL), TSH 0.9 IU/L SIunits (normal 0.4-4.0 IU/L SI units), a total testosterone of 65 ng/dl (normal 2.4-47 ng/dl), and glycated hemoglobin level of 6.1% (normal value ≤5.6%). Based on thisinformation, the APRN diagnoses the patient with polycystic ovarian syndrome (PCOS) andrefers her to the Women’s Health APRN for further workup and management.Question 1 of 2:What is the pathogenesis of PCOS?Answer:Polycystic ovary syndrome (PCOS) is a heterogeneous disorder characterized byhyperandrogenism and chronic anovulation. Depending on diagnostic criteria, 6% to20% of reproductive aged women are affected. PCOS presents as a phenotypereflecting a self-perpetuating vicious cycle involving neuroendocrine, metabolic, andovarian dysfunction. PCOS reflects the interactions among multiple proteins and genesinfluenced by epigenetic and environmental factors. Functional ovarianhyperandrogenism due to ovarian steroidal dysregulation is at the center of thepathogenesis of polycystic ovary syndrome. Functional ovarian hyperandrogenism dueto ovarian steroidal dysregulation is at the center of the pathogenesis of polycystic ovarysyndrome. This has both genetic and environmental factors. The genetic factors arepolycystic ovary morphology, insulin resistance, hyperandrogenemia, defects in insulinsecretion. The steroidal dysregulation may lead to anovulation, irregular menses,virilization, hirsutism and infertility. Insulin resistance may also occur.How does PCOS affect a woman’s fertility or infertility?Answer:Women with PCOS have hormonal imbalances showing increased levels oftestosterone. This hormonal imbalance prevents development and release of matureeggs. This prevents ovulation thus preventing pregnancy to occur.Question 2:

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Document Details

University
Walden University
Course
NURS 6501
Subject
Nursing

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