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Biology IB HL - 6.3 Disease Defences Part 4

Biology12 CardsCreated about 2 months ago

This deck covers key concepts related to disease defenses, focusing on the historical significance of penicillin, the nature and impact of HIV, and methods of transmission and prevention.

WHat is the historical significance of penicillin?

In 1945, Howard Florey, Ernst Chain and Alexander Fleming were collectively awarded the Nobel Prize for Medicine; Following the chemical determination of penicillin structure in 1945, several synthetic derivatives have since been created; These derivatives (including methicillin) offer many benefits including a broader spectrum, more stability and greater tolerance
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Key Terms

Term
Definition
WHat is the historical significance of penicillin?
In 1945, Howard Florey, Ernst Chain and Alexander Fleming were collectively awarded the Nobel Prize for Medicine; Following the chemical determination...
What is HIV?
The Human Immunodeficiency Virus (HIV) is a retrovirus that infects helper T cells, disabling the body’s adaptive immune system
What is HIV collectively classified as?
It causes a variety of symptoms and infections collectively classed as Acquired Immuno-Deficiency Syndrome (AIDS)
What does HIV target?
HIV specifically targets the helper T lymphocytes which regulate the adaptive immune system
After infection, what does the HIV virus undergo?
Following infection, the virus undergoes a period of inactivity (clinical latency) during which infected helper T cells reproduce
After a period of latency, what does the HIV virus do?
Eventually, the virus becomes active again and begins to spread, destroying the T lymphocytes in the process (lysogenic cycle)

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TermDefinition
WHat is the historical significance of penicillin?
In 1945, Howard Florey, Ernst Chain and Alexander Fleming were collectively awarded the Nobel Prize for Medicine; Following the chemical determination of penicillin structure in 1945, several synthetic derivatives have since been created; These derivatives (including methicillin) offer many benefits including a broader spectrum, more stability and greater tolerance
What is HIV?
The Human Immunodeficiency Virus (HIV) is a retrovirus that infects helper T cells, disabling the body’s adaptive immune system
What is HIV collectively classified as?
It causes a variety of symptoms and infections collectively classed as Acquired Immuno-Deficiency Syndrome (AIDS)
What does HIV target?
HIV specifically targets the helper T lymphocytes which regulate the adaptive immune system
After infection, what does the HIV virus undergo?
Following infection, the virus undergoes a period of inactivity (clinical latency) during which infected helper T cells reproduce
After a period of latency, what does the HIV virus do?
Eventually, the virus becomes active again and begins to spread, destroying the T lymphocytes in the process (lysogenic cycle)

HIV - what does a reduction in number of helper T cells cause?

lymphocytes in the process (lysogenic cycle)
With a reduction in the number of helper T cells, antibodies are unable to be produced, resulting in a lowered immunity

What does HIV result in, finally?
The body becomes susceptible to opportunistic infections, eventually resulting in death if the condition is not managed
How is HIV transmitted, generally?
HIV is transmitted through the exchange of body fluids (including unprotected sex, blood transfusions, breastfeeding, etc.)
How can the risk of HIV through sexual contact be reduced?
The risk of exposure to HIV through sexual contact can be minimised by using latex protection (i.e. condoms)
Can you be immune to HIV infection?
YES A small minority of people are immune to HIV infection (they lack the CD4+ receptor on TH cells that HIV requires for docking)
Where is HIV particularly prevalent?
HIV is a global issue, but is particularly prevalent in poorer nations with poor education and health systems