Cellular Respiration
This flashcard set explores the structure and function of mitochondria, highlighting its role in aerobic and anaerobic respiration. It explains key components such as the inner mitochondrial membrane and matrix, and introduces metabolic activity as a measure of biochemical processes in the cell.
Mitochondria
"Powerhouse" of the cell, organelle that produces ATP using the Citric Acid Cycle and Oxidative Phosphorylation when O2 is present

Key Terms
Mitochondria
"Powerhouse" of the cell, organelle that produces ATP using the Citric Acid Cycle and Oxidative Phosphorylation when O2 is present
Aerobic respiration
Cellular respiration that uses oxygen, producing about 32 ATP per molecule of glucose
Anaerobic respiration
Cellular respiration that uses glycolysis and fermentation when no oxygen is present, producing about 2 ATP per molecule of glucose
Inner mitochondrial membrane
The location of electron transport chains and ATP synthase, folded many times to increase surface area
Mitrochondria matrix
The innermost part of the mitochondria, high pH as H+ is pumped OUT of this space
Metabolic activity
The amount of metabolism occurring--the number of chemical reactions ongoing within an organism
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| Term | Definition |
|---|---|
Mitochondria | "Powerhouse" of the cell, organelle that produces ATP using the Citric Acid Cycle and Oxidative Phosphorylation when O2 is present |
Aerobic respiration | Cellular respiration that uses oxygen, producing about 32 ATP per molecule of glucose |
Anaerobic respiration | Cellular respiration that uses glycolysis and fermentation when no oxygen is present, producing about 2 ATP per molecule of glucose |
Inner mitochondrial membrane | The location of electron transport chains and ATP synthase, folded many times to increase surface area |
Mitrochondria matrix | The innermost part of the mitochondria, high pH as H+ is pumped OUT of this space |
Metabolic activity | The amount of metabolism occurring--the number of chemical reactions ongoing within an organism |
Respiring | When an organism is actively undergoing cellular respiration, intaking O2 and excreting CO2 |
pH | The concentration of H+ ions present, a lower number indicates more H+, a higher number indicates less H+ |
Proton (H+) pump | A protein transports H+ to generate an electrochemical gradient in order to power chemiosmosis |
Proton gradient | A difference in proton (H+ ion) concentration across a membrane that can be used as a source of energy |
Oxidative phosphorylation | The formation of ATP, in the presence of oxygen, by chemiosmosis using the electron transport chain and ATP synthase. It uses ADP and Pi |
Glycolysis | The process used to break down glucose into pyruvate in the cytoplasm of a cell, producing two ATP |
Krebs cycle/Citric acid cycle | The cyclical series of reactions used to break acetyl-CoA (from pyruvate) down to produce CO2, ATP, NADH, and FADH2 |
Electron transport chain | A series of proteins embedded in the inner mitochondrial membrane, they pump H+ ions as they pass energized electrons from one protein to the next |
ATP synthase | The protein in the inner mitochondrial membrane that uses energy from the movement of H+ down a proton gradient to convert ADP and Pi to ATP |
Fermentation | The process cells can use when oxygen isn't present, it recycles NADH in order to continue performing glycolysis |
Lactic acid/blood lactate | The waste product of fermentation in many types of cells, including human muscle cells |
Substrate-level phosphorylation | The transfer of phosphate group from a phosphorylated compound (substrate) directly to ADP to create ATP, WITHOUT using Pi. It occurs in glycolysis and the citric acid cycle |
Hypertonic environment | When the environment is more concentrated (has more ions) than the cytoplasm of the cell. The cell will shrink (and become skinny like a hyperactive kid) as water is lost |
Hypotonic environment | When the environment is less concentrated (fewer ions) than the cytoplasm of the cell. The cell will swell (and get fat like a hippo) as water is gained |
Consequence of too much water in a cell | A cell's membrane will explode from pressure |
Consequence of too little water | A cell will shrink, shriveling up and dying |
Isotonic | When the environment is the same concentration as the cell. A cell will neither gain or lose water. |
Inorganic phosphate | Pi, phosphate that isn't attached to anything |
Phosphorylation | The transfer of a phosphate group (usually from ATP) to a molecule. |
ATP synthesis | The production of ATP, using either substrate-level or oxidative phosphorylation |
NADH | An electron-carrier that is used to pass energized electrons to the electron transport chain. The reduced form of NAD+. Made in glycolysis, pyruvate oxidation, and the citric acid cycle |
FADH2 | An electron-carrier that is used to pass energized electrons to the electron transport chain. The reduced form of FAD. Made in the citric acid cycle. |
NAD+ | The oxidized, unenergized form of NADH |
Pyruvate | The product of glycolysis, a 3-carbon molecule |
Glucose | The 6-carbon sugar used in glycolysis |
Electron carrier | A molecule that can be used to store high energy electrons, to release them later at the electron transport chain |
Oxidization/oxidizing | When a molecule LOSES electrons and LOSES energy |
Reduction/reducing | When a molecule GAINS electrons and GAINS energy |
Cellular respiration formula | C₆H₁₂O₆ + 60₂ -> 6CO₂ + 6H₂0 + ATP |
Intermembrane space | The space between the inner and outer mitochondrial membrane, it has a low pH as many H+ ions are pumped into this area to create a proton gradient |
Pyruvate oxidation | The conversion of pyruvate into acetyl-CoA so it can be used in the citric acid cycle |
Acetyl-CoA | The molecule used to start the citric acid cycle |
Cytoplasm | The part of the cell where glycolysis occurs |