Histology - Connective Tissue Images
Embryonic connective tissue with sparse, star-shaped cells in a gel-like ground substance. Serves as the origin for all connective tissue types. Found in the umbilical cord (Wharton's jelly); rich in ground substance with few collagen fibers and fibroblasts. Loosely arranged collagen, elastic, and reticular fibers. Trichrome stain highlights collagen in blue/green, making fiber distribution and cell types easy to identify.

Mesenchyme
Key Terms
Mesenchyme
Mucous Connective Tissue
Loose (areolar) connective tissue (LCT) - trichrome
Dense Regular Connective Tissue (DRCT) - H&E
Dense Irregular Connective Tissue (DiRCT)
Loose (areolar) connective tissue (LCT) - H&E stain
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| Term | Definition |
|---|---|
Mesenchyme | |
Mucous Connective Tissue | |
Loose (areolar) connective tissue (LCT) - trichrome | |
Dense Regular Connective Tissue (DRCT) - H&E | |
Dense Irregular Connective Tissue (DiRCT) | |
Loose (areolar) connective tissue (LCT) - H&E stain | |
Loose (areolar) connective tissue (LCT) - trichrome stain | |
Reticular Tissue | |
White and Brown Fat | |
Loose (areolar) CT | |
White Adipose Tissue - H&E | |
Elastic Fibers | |
Elastic fibers interwoven with collagen fibers. | |
(Collagen) Fibrils (f) in cross-section & longitudinal section exhibiting periodicity (68nm). | |
Type III Collagen - reticular fibers. Stained black by silver (argyrophilic). | |
Reticular fibers in lymph node. Delicate latticework, sliver stain. | |
Type VII Collagen. Anchors basal lamina to reticular lamina. | |
Fibroblast (LM) | |
Fibroblast (TEM) | |
Activated fibroblast | |
Fibrocyte (quiescent) | |
Myofibril | |
Activated fibroblast copy | |
Macrophage (LM view) | |
Macrophage (TEM view) (phagocytotic cell) | |
Foreign Body Giant Cells. AKA Multinucleated Giant Body Cells | |
Foreign Body Giant Cells. AKA Multinucleated Giant Body Cells | |
Mast Cell (TEM). Central nucleus, filled with electron dense secretory granules. | |
Unilocular Adipocyes | |
Multilocular (brown) fat cells | |
Multilocular Adipocytes (LM, H&E stain) | |
Multilocular Adipocytes (TEM) | |
Lymphocyte - size of RBC, round nucleus, thin rim of cytoplasm | |
Plasma cell - antibody production | |
White blood cells | |
Connective Tissue Embryonic Origins | |
Plasma cell (LM), clockface heterochromatin. | |
Plasma Cell | |
Mucosa = Epithelium + Lamina propria | |
Multilocular adipocyte | |
Mucous glands (exocrine glands, arrows = lumen) | |
Loose (areolar) connective tissue (LCT) - H&E stain |