QQuestionBiochemistry
QuestionBiochemistry
"Fill in the blank:
To cause cancer, proto-oncogenes require _____ allele(2$) to be mutated and therefore are considered ________. The mutation results in a ___ of function."
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Answer
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Step 1:I'll solve this genetics problem step by step:
Step 2:: Understand Proto-oncogene Characteristics
Proto-oncogenes are genes that, when functioning normally, help regulate cell growth and division. When mutated, they can potentially contribute to cancer development.
Step 3:: Number of Alleles Required for Mutation
Proto-oncogenes are considered $$recessive$$.
This means that to cause cancer, 1 allele needs to be mutated.
Step 4:: Functional Change
When a proto-oncogene is mutated, it results in a $$gain$$ of function, which means the gene becomes overactive and promotes uncontrolled cell growth.
Final Answer
- Number of alleles required to cause cancer: 1 - Classification: recessive - Mutation results in: gain of function The complete answer fills in the blanks as follows: "To cause cancer, proto-oncogenes require 1 allele(s) to be mutated and therefore are considered recessive. The mutation results in a gain of function."
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