QQuestionBiology
QuestionBiology
"Select the true statements about dopamine.
L‑dopa is converted to dopamine once inside the brain.
Dopamine cannot cross the blood–brain barrier.
Dopamine deficiency causes Parkinson's disease.
Administration of dopamine can treat the symptoms of Parkinson's disease.
Dopamine is a membrane transport protein located in the blood–brain barrier."
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Answer
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Step 1:: Identify the true statements about dopamine.
L-dopa is a precursor to dopamine, and it can cross the blood-brain barrier. Once inside the brain, L-dopa is converted to dopamine. Therefore, the statement "L-dopa is converted to dopamine once inside the brain" is true.
Step 2::
Dopamine itself cannot cross the blood-brain barrier, so the statement "Dopamine cannot cross the blood–brain barrier" is true.
Step 3::
Parkinson's disease is associated with a deficiency in dopamine in certain areas of the brain. Therefore, the statement "Dopamine deficiency causes Parkinson's disease" is a simplification and not entirely accurate. A more accurate statement would be "A deficiency in dopamine in specific areas of the brain contributes to the development of Parkinson's disease."
Step 4::
Since dopamine cannot cross the blood-brain barrier, administering dopamine would not be an effective treatment for Parkinson's disease. Instead, L-dopa is administered, which can cross the blood-brain barrier and be converted to dopamine once inside the brain. Therefore, the statement "Administration of dopamine can treat the symptoms of Parkinson's disease" is false.
Step 5::
Dopamine is a neurotransmitter and not a membrane transport protein. Membrane transport proteins are responsible for the movement of molecules across cell membranes. Therefore, the statement "Dopamine is a membrane transport protein located in the blood–brain barrier" is false.
Final Answer
The true statements about dopamine are: - L-dopa is converted to dopamine once inside the brain. - Dopamine cannot cross the blood-brain barrier. A more accurate statement regarding Parkinson's disease is: - A deficiency in dopamine in specific areas of the brain contributes to the development of Parkinson's disease.
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