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Building DNA Gizmo - Document preview page 1

Building DNA Gizmo - Page 1

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Building DNA Gizmo

Explore DNA structure and replication with this interactive activity. Learn key terms like double helix, nucleotide, and mutation. Understand how DNA copies itself by breaking base pair bonds.

Alice Edwards
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Building DNA Gizmo - Page 1 preview imageName:Dale:10/14/21Student Exploration: Building DNADirections: Follow the instructions to go through the simulation. Respond to the questions andprompts in the orange boxes.Vocabulary:double helix. DNA. enzyme, mutation, nitrogenous base, nucleoside, nucleotide, replicationPrior Knowledge Questions (Do these BEFORE usingtheGizmo.)DNAis an incredible molecule that forms the basis of life on Earth.DNAmolecules contain instructions forbuilding every living organism on Earth, from the tiniesl bacterium to a massive blue whale. DNA also haslheability Ioreplicate,or make copies of itself. This allows living things to grow and reproduce.1.Lookalthe DNAmolecule shownat right. What does it look like?A figure 8 like shape and a double helixThis shape is called adoublehelix2.Based on this picture how do youthinka DNA molecule makes a copy of itself?(Hint: Lookatthe bottom two "rungs" oflheladder.)By breaking the bonds that connect the linkedbasesGizmo Warm-upThe fid/j/dingDNAGizmo allowsyoutoconstructaDNAmolecule and gothroughthe process ofDNAreplication Examinethe components thatmakeupa DNA molecule.1.What are the Iwo DNA components shown in the Gizmo?deoxyribose and a nitrogenous base.2.A nucleoside has two partsa pentagonal sugar (deoxyribose) and anitrogenous base (incolor). When a nucleoside is joined Io a phosphate, itis called a nucleotideHow many different nitrogenous bases do you see?Note: The names of these nitrogenous bases are adenine (red), cytosine (yellow), guanine (blue), andthymine (green).
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Building DNA Gizmo - Page 2 preview imageGet the Gizmo ready:If necessary, click Reset Io start Ihe buildingprocess.sfa: BActivity A:Build a DMA moleculeQuestion: What is the structure of DMA?Paste the image below, and label this imageOriginal DNA molecule/Lett sideRighl side1.BuildFollow the steps given in the Gizmo toconstruct a molecule of ONA. (Note: For simplicity .this DNA molecule is shown in Iwo dimensions,without Ihe twist.)Stop when the hinI reads: "The DNA molecule iscomplete." In thespaces at right, lislthe sequence ofnitrogenous bases onthe left-hand side ofthe DNA molecule3 ujand Ihe righl-handiside.3 .?-Tl i tT2.Take a picture:Click the camera (O )Io take a snapshot of your DNA moleculeRight-click the image and select Copy ImageATCGATCGTAGC3.Explain Describe the structure of the DNA molecule you made.A.What makes up the sides of the DNA molecule?phosphates anddeoxyribose sugarB.Whal makes up the "rungs" of the DNA molecule?pairs of nitrogenous bases4.Fill in: Write the name of the nitrogenous base thal joins Io each of Ihe bases below:Adenine (A) joins IoThymineThymine (T) joins toAdenineCylosine (C) joins IoGuanineGuanine (G) joins toCyostine5.Practice: The left side of a DNA molecule is shown.Dratv a complementary right side of the molecule.Eithtw hand draw orr-cnola EDIT !use Ihe drawing tool6.Challenge. This DNA slrand consists of eight pairs ofnitrogenous bases. How many different sequences of eightbases can you make? Explain how you found your answer.Reproduction Far educational use only. Ruble sharing or pasting prohtirted. O2Q2D Ex
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