ATI Pharmacology Proctored Test Bank with Answers (313 Solved Questions)

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ATI Pharmacology ProctoredTest Bank1.1) A nurse is caring for a client withhyperparathyroidism and notes that theclient's serum calcium level is 13 mg/dL.Which medication should the nurse prepareto administer as prescribed to theclient?1.Calciumchloride2.Calciumgluconate3.Calcitonin(Miacalcin)4.Large doses ofvitaminD2.2.)Oralironsupplementsareprescribedfora 6-year-old child withirondeficiencyanemia.Thenurse instructs the mothertoadminister theironwith whichbest fooditem?1.Milk2.Water3.Applejuice4.Orangejuice3.3.)Salicylicacidisprescribedforaclientwith a diagnosis ofpsoriasis.Thenursemonitorstheclient,knowingthatwhichofthefollowingwouldindicatethepresenceofsystemictoxicityfromthismedication?1.Tinnitus2.Diarrhea3.Constipation4.Decreasedrespirations4.4.) The camp nurse asks the childrenpreparing to swim in the lake if they haveapplied sunscreen. The nurse reminds thechildren that chemical sunscreens are mosteffective when applied:1.Immediately beforeswimming2.15minutesbeforeexposuretothesun3.Immediatelybeforeexposuretothesun4.Atleast30minutes beforeexposuretothesun5.5.) Mafenide acetate (Sulfamylon) isprescribed for the client with a burn injury.When applying the medication, the clientcomplains of local discomfort and burning.Which of the following is the mostappropriate nursing action?1.Notifying the registerednurse2.Discontinuing themedication3.Informing the client that this isnormal4.Applyingathinnerfilmthanprescribedtotheburnsite3.Calcitonin(Miacalcin)Rationale:Thenormalserumcalciumlevelis8.6to10.0mg/dL.Thisclientisexperiencinghypercalcemia.Calciumgluconateandcalciumchloridearemedicationsusedforthetreatmentoftetany,which occurs as aresultof acute hypocalcemia. Inhypercalcemia,largedosesofvitaminDneedtobeavoided.Calcitonin,athyroidhormone,decreasestheplasma calcium level by inhibiting boneresorptionandloweringtheserumcalciumconcentration.4.OrangejuiceRationale:Vitamin Cincreases theabsorption ofironbythebody.Themothershould beinstructedtoadministerthemedicationwithacitrusfruitorajuicethatishighinvitaminC.Milkmayaffectabsorptionoftheiron.Waterwillnotassistinabsorption.OrangejuicecontainsagreateramountofvitaminCthanapplejuice.1. TinnitusRationale:Salicylicacidisabsorbedreadilythroughtheskin,andsystemictoxicity(salicylism)canresult.Symptomsincludetinnitus,dizziness,hyperpnea,andpsychologicaldisturbances.Constipationanddiarrheaarenotassociatedwithsalicylism.4.Atleast30minutesbeforeexposuretothesunRationale:Sunscreensaremosteffectivewhenappliedatleast30minutesbeforeexposuretothesunsothattheycanpenetratetheskin.Allsunscreensshouldbereappliedafterswimming orsweating.3.InformingtheclientthatthisisnormalRationale:Mafenideacetateisbacteriostaticforgram-negativeandgram-positiveorganismsandisusedtotreatburnstoreducebacteriapresentinavasculartissues.Theclientshouldbeinformedthatthemedicationwillcauselocaldiscomfortandburningandthatthisisanormalreaction;thereforeoptions1,2,and4areincorrect

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6.6.)The burnclient is receiving treatments oftopicalmafenideacetate(Sulfamylon)tothesite ofinjury. Thenurse monitors theclient,knowingthatwhichofthefollowingindicatesthat a systemiceffecthasoccurred?1.Hyperventilation2.Elevated blood pressure3.Local pain at the burn site4.Local rash at the burn site7.7.) Isotretinoin is prescribed for a client withsevere acne. Before the administration of thismedication, the nurse anticipates that whichlaboratory test will be prescribed?1.Plateletcount2.Triglyceridelevel3.Complete bloodcount4.White blood cellcount8.8.) A client with severe acne is seen intheclinic and the health care provider (HCP)prescribes isotretinoin. The nurse reviews theclient's medication record and would contactthe (HCP) if the client is taking whichmedication?1.VitaminA2.Digoxin(Lanoxin)3.Furosemide(Lasix)4.Phenytoin(Dilantin)9.9.)Thenurse is applying a topicalcorticosteroidtoa client with eczema.Thenurse would monitor for the potential forincreased systemic absorption of themedication if the medication were beingappliedtowhichofthefollowingbodyareas?1.Back2.Axilla3.Soles of thefeet4.Palmsof thehands10.10.) The clinic nurse is performing anadmission assessment on a client. The nursenotes that the client is taking azelaic acid(Azelex). Because of the medicationprescription, the nurse wouldsuspect that theclient is being treated for:1.Acne2.Eczema3.Hairloss4.Herpessimplex1.HyperventilationRationale:Mafenideacetateisacarbonicanhydraseinhibitorandcansuppressrenalexcretionof acid,therebycausing acidosis. Clientsreceivingthistreatmentshould bemonitoredforsignsofanacid-baseimbalance(hyperventilation).Ifthisoccurs,themedicationshouldbediscontinuedfor1to2days.Options3and4describelocalratherthansystemiceffects.Anelevatedbloodpressuremaybeexpectedfromthepainthatoccurswithaburninjury.2.Triglyceride levelRationale:Isotretinoincanelevatetriglyceridelevels.Bloodtriglyceridelevelsshouldbemeasuredbeforetreatmentand periodicallythereafteruntiltheeffectonthetriglycerideshasbeenevaluated.Options1,3,and4donotneedtobemonitoredspecifically during thistreatment.1.VitaminARationale:IsotretinoinisametaboliteofvitaminAandcanproducegeneralizedintensificationofisotretinoin toxicity.Because ofthe potential for increased toxicity,vitamin Asupplementsshouldbediscontinuedbeforeisotretinointherapy.Options2,3,and4arenotcontraindicatedwiththeuseofisotretinoin.2.AxillaRationale:Topicalcorticosteroidscanbeabsorbedintothesystemiccirculation.Absorptionishigherfromregionswheretheskin is especially permeable (scalp, axilla,face,eyelids,neck,perineum,genitalia),andlowerfromregionsinwhichpermeabilityispoor (back, palms,soles).1.AcneRationale:Azelaicacidisatopicalmedicationusedtotreatmildtomoderateacne.Theacidappearstowork by suppressingthegrowthofPropionibacterium acnesanddecreasingtheproliferationofkeratinocytes.Options2,3,and4areincorrect.

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11.11.)Thehealth care providerhasprescribed silversulfadiazine (Silvadene) for the client withapartial-thicknessburn,whichhasculturedpositiveforgram-negative bacteria.Thenurse is reinforcinginformationtotheclientaboutthemedication.Whichstatementmadeby the client indicatesalack ofunderstandingaboutthetreatments?1."Themedication is anantibacterial."2."Themedicationwill help heal theburn."3."Themedicationwillpermanentlystainmyskin."4."Themedicationshouldbe applied directlytothewound."12.12.)Anurseiscaringforaclientwhoisreceivinganintravenous (IV) infusion of an antineoplasticmedication.Duringtheinfusion,theclientcomplainsofpainat the insertion site. During an inspection ofthe site, the nursenotesredness and swelling andthat the rate of infusion of the medicationhasslowed.Thenurseshouldtake whichappropriateaction?1.Notify the registerednurse.2.Administerpainmedicationtoreducethediscomfort.3.Apply ice and maintain the infusion rate, asprescribed.4.ElevatetheextremityoftheIVsite,andslowtheinfusion.13.13.) The client with squamous cell carcinoma of thelarynx is receiving bleomycin intravenously. Thenurse caringforthe client anticipates that whichdiagnostic study will be prescribed?1.Echocardiography2.Electrocardiography3.Cervicalradiography4.Pulmonary functionstudies14.14.) The client with acute myelocytic leukemia isbeing treated with busulfan (Myleran). Whichlaboratory value would the nurse specificallymonitor during treatment with this medication?1.Clottingtime2.Uricacidlevel3.Potassiumlevel4.Blood glucoselevel3."Themedicationwillpermanentlystainmyskin."Rationale:Silversulfadiazine(Silvadene)isanantibacterialthathasabroadspectrumofactivityagainstgram-negativebacteria,gram-positivebacteria,andyeast.Itisapplieddirectlytothewoundtoassistinhealing.Itdoesnotstaintheskin.1.Notifytheregisterednurse.Rationale:When antineoplastic medications(Chemotheraputic Agents)areadministeredviaIV,greatcaremustbetakentopreventthemedicationfromescapingintothetissuessurroundingtheinjectionsite,becausepain,tissuedamage, andnecrosiscanresult.The nurse monitorsforsigns ofextravasation,such asrednessor swelling attheinsertion site and adecreasedinfusionrate.Ifextravasationoccurs,theregisterednurseneedstobenotified;heorshewillthencontactthehealthcareprovider.4. Pulmonary function studiesRationale:Bleomycinisanantineoplasticmedication(ChemotheraputicAgents)thatcancauseinterstitialpneumonitis,whichcanprogresstopulmonaryfibrosis.Pulmonaryfunctionstudiesalongwithhematological,hepatic,andrenalfunction testsneedtobemonitored.The nurseneedstomonitor lungsoundsfordyspneaandcrackles,whichindicatepulmonarytoxicity.Themedicationneedstobe discontinued immediately if pulmonary toxicityoccurs. Options1, 2,and 3areunrelatedto thespecific use of thismedication.2.Uric acidlevelRationale:Busulfan(Myleran)can cause anincreaseintheuric acid level.Hyperuricemiacanproduceuricacidnephropathy,renalstones,andacuterenalfailure.Options1,3,and 4arenot specificallyrelatedtothismedication.

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15.15.) The client with small cell lung cancer isbeing treated with etoposide (VePesid). Thenurse who is assisting in caringforthe clientduring its administration understands that whichside effect is specifically associated with thismedication?1.Alopecia2.Chestpain3.Pulmonaryfibrosis4.Orthostatichypotension16.16.)Theclinicnurseisreviewingateachingplanfor the client receiving an antineoplasticmedication. When implementing the plan, thenurse tells theclient:1.Totakeaspirin(acetylsalicylic acid) asneededforheadache2.Drink beverages containing alcohol inmoderate amounts eachevening3.Consultwithhealthcareproviders(HCPs)before receivingimmunizations4.Thatit is not necessarytoconsult HCPsbeforereceivingafluvaccineatthelocalhealthfair17.17.) The client with ovarian cancer is beingtreated with vincristine (Oncovin). The nursemonitors the client, knowing that which of thefollowing indicates a side effect specificto thismedication?1.Diarrhea2.Hairloss3.Chestpain4.Numbness and tingling in the fingers andtoes18.18.)Thenurse is reviewing thehistoryandphysical examination of a client who will bereceivingasparaginase(Elspar),anantineoplastic agent.Thenurse consults withthe registered nurse regarding theadministration of the medication if which of thefollowing is documented in the client'shistory?1.Pancreatitis2.Diabetes mellitus3.Myocardial infarction4.Chronicobstructive pulmonarydisease4. Orthostatic hypotensionRationale:Asideeffectspecifictoetoposideisorthostatichypotension.Theclient'sbloodpressureismonitoredduringtheinfusion.Hairlossoccurswithnearlyalltheantineoplasticmedications.Chestpainandpulmonaryfibrosisareunrelatedtothismedication.3.Consultwithhealthcareproviders(HCPs)beforereceivingimmunizationsRationale:Becauseantineoplasticmedicationslowertheresistanceofthebody,clientsmustbeinformednottoreceiveimmunizationswithoutaHCP'sapproval.Clientsalsoneedtoavoid contact with individuals who haverecently receiveda live virusvaccine.Clientsneedtoavoidaspirinandaspirin-containingproductstominimizetherisk of bleeding, andtheyneedtoavoid alcoholtominimizetherisk oftoxicity and sideeffects.4.NumbnessandtinglinginthefingersandtoesRationale:A sideeffectspecifictovincristine isperipheralneuropathy,which occurs inalmosteveryclient.Peripheralneuropathycanbemanifestedasnumbnessandtinglinginthefingersandtoes.DepressionoftheAchillestendonreflexmaybethefirstclinicalsignindicatingperipheralneuropathy.Constipationratherthandiarrheaismostlikelytooccurwiththismedication,althoughdiarrheamayoccuroccasionally.Hairlossoccurswithnearlyalltheantineoplasticmedications.Chest pain is unrelated to this medication.1.PancreatitisRationale:Asparaginase(Elspar)iscontraindicatedifhypersensitivityexists,inpancreatitis,oriftheclient has a history ofpancreatitis.The medication impairspancreaticfunctionandpancreaticfunctiontestsshouldbeperformedbeforetherapybeginsandwhenaweekormorehaselapsedbetweenadministrationofthedoses.Theclientneedstobemonitoredforsigns ofpancreatitis,which include nausea,vomiting,andabdominalpain.Theconditionsnotedinoptions2,3,and4arenotcontraindicatedwith thismedication.

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19.19.)Tamoxifenis prescribedfortheclient with metastatic breastcarcinoma.Thenurse understandsthat theprimaryactionofthismedication is to:1.IncreaseDNAandRNAsynthesis.2.Promote thebiosynthesisofnucleicacids.3.Increase estrogenconcentration and estrogenresponse.4.Compete with estradiol forbindingtoestrogen in tissuescontaininghighconcentrations ofreceptors.20.20.)Theclient with metastaticbreast cancer is receivingtamoxifen.Thenurse specificallymonitors which laboratoryvaluewhile the client is taking thismedication?1.Glucoselevel2.Calciumlevel3.Potassiumlevel4.Prothrombintime21.21.)Anurseisassistingwithcaringfor a client with cancer who isreceiving cisplatin.Selecttheadverseeffectsthat the nursemonitors for thatareassociatedwith this medication.Selectallthatapply.1.Tinnitus2.Ototoxicity3.Hyperkalemia4.Hypercalcemia5.Nephrotoxicity6.Hypomagnesemia22.22.)Anurseiscaringforaclientafter thyroidectomy andnotesthat calcium gluconate isprescribed for the client.Thenurse determines that thismedicationhasbeen prescribedto:1.Treatthyroidstorm.2.Preventcardiacirritability.3.Treathypocalcemictetany.4.Stimulate the releaseofparathyroidhormone.4.Competewithestradiolforbindingtoestrogenintissuescontaininghighconcentrationsofreceptors.Rationale:Tamoxifenisanantineoplasticmedicationthatcompeteswithestradiolforbindingtoestrogenintissuescontaininghighconcentrationsofreceptors.Tamoxifenisusedtotreatmetastaticbreastcarcinomainwomenandmen.Tamoxifenisalsoeffectiveindelayingtherecurrenceofcancerfollowingmastectomy.TamoxifenreducesDNAsynthesisandestrogenresponse.2.CalciumlevelRationale:Tamoxifenmayincreasecalcium,cholesterol,andtriglyceridelevels.Beforetheinitiationoftherapy,a complete bloodcount,plateletcount,and serum calcium levels should beassessed. These blood levels, along withcholesteroland triglyceride levels, should bemonitoredperiodicallyduringtherapy.Thenurseshouldassessforhypercalcemiawhiletheclientistakingthismedication.Signsofhypercalcemiaincludeincreasedurinevolume,excessivethirst,nausea,vomiting,constipation,hypotonicityofmuscles,anddeepboneandflankpain.1.Tinnitus2.Ototoxicity5.Nephrotoxicity6.HypomagnesemiaRationale:Cisplatinisanalkylatingmedication.Alkylatingmedicationsarecellcyclephase-nonspecificmedicationsthataffectthesynthesisofDNAbycausingthecross-linkingofDNAtoinhibitcellreproduction.Cisplatin may causeototoxicity,tinnitus, hypokalemia, hypocalcemia,hypomagnesemia,andnephrotoxicity.Amifostine(Ethyol)maybeadministeredbeforecisplatintoreducethe potential forrenaltoxicity.3.Treathypocalcemictetany.Rationale:Hypocalcemia candevelopafterthyroidectomyiftheparathyroidglandsareaccidentallyremovedorinjuredduringsurgery.Manifestationsdevelop1to7daysaftersurgery.Iftheclientdevelopsnumbnessandtinglingaroundthemouth,fingertips,ortoesormusclespasmsortwitching,thehealthcareproviderisnotifiedimmediately.Calciumgluconateshouldbekeptatthebedside.

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23.23.) A client whohasbeennewlydiagnosed with diabetes mellitushasbeenstabilizedwithdailyinsulininjections.Whichinformationshouldthe nurse teach when carryingoutplans fordischarge?1.Keepinsulinvialsrefrigeratedatalltimes.2.Rotate the insulin injectionsitessystematically.3.Increasetheamountofinsulinbeforeunusualexercise.4.Monitortheurineacetoneleveltodeterminetheinsulindosage.24.24.)Anurseisreinforcingteachingfor a client regardinghowtomixregular insulin and NPH insulin inthesamesyringe. Which of thefollowing actions, if performed bythe client, indicates theneedforfurtherteaching?1.Withdraws the NPH insulinfirst2.Withdrawstheregularinsulinfirst3.InjectsairintoNPHinsulinvialfirst4.Injectsanamountofairequaltothedesireddoseofinsulinintothevial25.25.) A home care nurse visits aclient recently diagnosed withdiabetes mellitus who is takingHumulin NPH insulindaily. Theclient asks the nurse how to storethe unopened vials of insulin. Thenurse tells the client to:1.Freeze theinsulin.2.Refrigerate theinsulin.3.Store the insulin in adark,dryplace.4.Keeptheinsulinatroomtemperature.26.26.)Glimepiride(Amaryl) isprescribedforaclientwithdiabetesmellitus. A nurse reinforcesinstructions for the client and tellsthe clienttoavoidwhich of thefollowing while taking thismedication?1.Alcohol2.Organmeats3.Whole-graincereals4.Carbonatedbeverages2.Rotatetheinsulininjectionsitessystematically.Rationale:Insulindosagesshouldnotbeadjustedorincreasedbeforeunusualexercise.Ifacetoneisfoundintheurine,itmaypossiblyindicatetheneedforadditionalinsulin.Tominimizethediscomfortassociatedwithinsulininjections,theinsulinshouldbeadministeredatroomtemperature.Injectionsitesshouldbesystematicallyrotatedfromoneareatoanother.Theclientshouldbeinstructedtogiveinjectionsinonearea,about1inchapart,untilthewholeareahasbeenusedandthentochangetoanothersite.Thispreventsdramaticchangesindaily insulinabsorption.1.WithdrawstheNPHinsulinfirstRationale:Whenpreparingamixtureofregularinsulin withanotherinsulinpreparation,theregularinsulinisdrawnintothesyringefirst.Thissequencewillavoidcontaminatingthevialofregularinsulinwithinsulinofanothertype.Options2,3,and4identifythecorrectactionsforpreparingNPH andregularinsulin.2.Refrigeratetheinsulin.Rationale:Insulininunopenedvialsshouldbestoredunderrefrigerationuntilneeded.Vialsshouldnotbefrozen.Whenstoredunopenedunderrefrigeration,insulincanbeuseduptotheexpirationdateonthevial.Options1,3,and4areincorrect.1.AlcoholRationale:Whenalcoholiscombinedwithglimepiride(Amaryl),adisulfiram-likereactionmayoccur.Thissyndromeincludesflushing,palpitations,andnausea.Alcoholcanalsopotentiatethehypoglycemiceffectsofthemedication. Clientsneedtobe instructedtoavoid alcoholconsumptionwhiletakingthismedication.Theitemsinoptions2,3,and4donotneedtobeavoided.

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27.27.)Sildenafil(Viagra)is prescribedtotreat a clientwith erectile dysfunction. A nurse reviews theclient's medical record and would question theprescription if which of the following isnotedin theclient's history?1.Neuralgia2.Insomnia3.Useofnitroglycerin4.Useofmultivitamins28.28.)Thehealth care provider (HCP) prescribesexenatide(Byetta)foraclientwithtype1diabetesmellitus who takes insulin.Thenurse knows thatwhich of the following is theappropriateintervention?1.Themedicationisadministeredwithin60minutesbefore the morning and eveningmeal.2.ThemedicationiswithheldandtheHCPiscalledtoquestion the prescription for theclient.3.Theclientismonitoredforgastrointestinalsideeffectsafteradministrationofthemedication.4.TheinsuliniswithdrawnfromthePenletintoaninsulin syringetoprepare foradministration.29.29.)A client is takingHumulinNPH insulin dailyevery morning.Thenurse reinforces instructions forthe client and tells the client that the most likelytimeforahypoglycemicreactiontooccuris:1.2to4hoursafteradministration2.4to12hoursafteradministration3.16to18hoursafteradministration4.18to24hoursafteradministration30.30.) A client with diabetes mellitusvisitsa healthcare clinic.Theclient's diabetes mellituspreviouslyhadbeen well controlled with glyburide (DiaBeta)daily, butrecently the fasting blood glucose levelhasbeen180to200mg/dL.Which medication, ifaddedtothe client's regimen,mayhavecontributedtothehyperglycemia?1.Prednisone2.Phenelzine(Nardil)3.Atenolol(Tenormin)4.Allopurinol(Zyloprim)3.UseofnitroglycerinRationale:Sildenafil(Viagra)enhancesthevasodilatingeffectofnitricoxideinthecorpuscavernosumofthepenis,thussustaininganerection.Becauseoftheeffectofthemedication,itiscontraindicatedwithconcurrentuseoforganicnitratesandnitroglycerin.Sildenafilisnotcontraindicatedwiththeuseofvitamins.Neuralgiaandinsomniaaresideeffectsofthemedication.2.ThemedicationiswithheldandtheHCPiscalledtoquestiontheprescription for theclient.Rationale:Exenatide(Byetta)isanincretinmimeticusedfortype2diabetesmellitusonly.Itisnotrecommendedforclientstakinginsulin.Hence,thenurseshould holdthemedication and questiontheHCPregardingthisprescription.Althoughoptions1and3arecorrectstatementsaboutthemedication,inthissituationthemedicationshouldnotbeadministered.Themedication ispackagedinprefilled pensreadyforinjection withouttheneedfordrawingitupintoanothersyringe.2.4to12hoursafteradministrationRationale:HumulinNPHisanintermediate-actinginsulin.Theonsetofactionis1.5hours,itpeaksin4to12hours,anditsdurationofactionis24hours.Hypoglycemic reactions most likely occur during peak time.1.PrednisoneRationale:Prednisonemaydecreasetheeffectoforalhypoglycemics, insulin,diuretics,andpotassiumsupplements.Option2,amonoamineoxidaseinhibitor,andoption3,aβ-blocker,havetheirownintrinsichypoglycemicactivity.Option 4decreasesurinaryexcretionof sulfonylurea agents,causingincreasedlevels oftheoralagents, which can leadtohypoglycemia.

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31.31.) A community health nursevisitsaclient at home. Prednisone 10 mg orallydailyhasbeen prescribed for the clientand the nurse reinforces teaching forthe clientaboutthe medication. Whichstatement, ifmadeby the client,indicates that further teaching isnecessary?1."Icantakeaspirinormyantihistamineif Ineedit."2."Ineedtotake the medication everydayat thesametime."3."Ineedtoavoidcoffee, tea, cola, andchocolate in mydiet."4."IfIgainmorethan5poundsaweek,I will call mydoctor."32.32.) Desmopressin acetate(DDAVP)isprescribedforthetreatmentofdiabetesinsipidus.Thenurse monitors the clientafter medication administration forwhich therapeuticresponse?1.Decreasedurinaryoutput2.Decreased bloodpressure3.Decreased peripheraledema4.Decreased blood glucoselevel33.33.)Thehomehealth care nurse isvisiting a client who was recentlydiagnosedwithtype2diabetesmellitus.Theclient is prescribedrepaglinide(Prandin)andmetformin(Glucophage)andasksthe nursetoexplainthesemedications.Thenurseshouldreinforcewhich instructionstothe client?Selectall thatapply.1.Diarrhea can occur secondarytothemetformin.2.Therepaglinideisnottakenifamealis skipped.3.Therepaglinideistaken30minutesbeforeeating.4.Candyoranothersimplesugariscarried and usedtotreat mildhypoglycemiaepisodes.5.Metformin increaseshepatic glucoseproductiontoprevent hypoglycemiaassociated withrepaglinide.6.Musclepainisanexpectedsideeffectof metformin andmaybe treated withacetaminophen(Tylenol).1."IcantakeaspirinormyantihistamineifIneedit."Rationale:Aspirinandotherover-the-countermedicationsshouldnotbetakenunlesstheclientconsultswiththehealthcareprovider(HCP).Theclientneedstotakethemedicationatthesametimeeverydayandshouldbeinstructednottostopthemedication.Aslightweightgainasaresultofanimprovedappetiteisexpected,butafterthedosageisstabilized,aweightgainof5lbormoreweeklyshouldbereportedtotheHCP.Caffeine-containingfoodsandfluidsneedtobeavoidedbecausetheymaycontributetosteroid-ulcerdevelopment.1.DecreasedurinaryoutputRationale:Desmopressinpromotesrenalconservationofwater.Thehormonecarriesoutthisactionbyactingonthecollectingductsofthekidneytoincreasetheirpermeabilitytowater,whichresultsinincreasedwaterreabsorption.Thetherapeuticeffectofthismedicationwouldbemanifestedbyadecreasedurineoutput.Options2,3,and4areunrelatedtotheeffectsof thismedication.1.Diarrheacanoccursecondarytothemetformin.2.Therepaglinideisnottakenifamealisskipped.3.Therepaglinideistaken30minutesbeforeeating.4.Candyoranothersimplesugariscarriedandusedtotreatmildhypoglycemiaepisodes.Rationale:Repaglinideisarapid-actingoralhypoglycemicagentthatstimulatespancreaticinsulinsecretionthatshouldbetakenbeforemeals,andthatshouldbewithheldiftheclientdoesnoteat.Hypoglycemiaisasideeffectofrepaglinideandtheclientshouldalwaysbepreparedbycarryingasimplesugarwithherorhimatalltimes.Metforminisanoralhypoglycemicgivenincombinationwithrepaglinideandworksbydecreasinghepaticglucoseproduction.Acommonsideeffectofmetforminisdiarrhea.Musclepainmayoccurasanadverseeffectfrommetforminbutitmightsignifyamoreseriousconditionthatwarrantshealthcareprovidernotification,nottheuseofacetaminophen.

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34.34.) A client withCrohn'sdisease isscheduledtoreceive an infusion ofinfliximab(Remicade).Thenurseassistingincaringfortheclientshouldtakewhichactiontomonitor the effectiveness oftreatment?1.Monitoringtheleukocytecountfor2daysafter theinfusion2.Checking the frequency and consistencyof bowelmovements3.Checkingserumliverenzymelevelsbefore and after theinfusion4.CarryingoutaHematestongastricfluidsafter theinfusion iscompleted35.35.)TheclienthasaPRNprescriptionforloperamidehydrochloride(Imodium).Thenurseunderstandsthatthismedicationisused for whichcondition?1.Constipation2.Abdominalpain3.An episode ofdiarrhea4.Hematest-positivenasogastric tubedrainage36.36.)Theclienthasa PRN prescription forondansetron(Zofran).Forwhichconditionshouldthismedicationbeadministeredtothe postoperativeclient?1.Paralyticileus2.Incisionalpain3.Urinaryretention4.Nausea andvomiting37.37.)Theclienthasbegun medication therapywith pancrelipase(Pancrease MT).Thenurseevaluates that the medication ishavingtheoptimalintendedbenefit if whicheffectisobserved?1.Weightloss2.Reliefofheartburn3.Reduction ofsteatorrhea4.Absence of abdominalpain38.38.)Anolderclientrecentlyhasbeentakingcimetidine(Tagamet).Thenursemonitorstheclient for which most frequent centralnervous systemsideeffectof thismedication?1.Tremors2.Dizziness3.Confusion4.Hallucinations2.CheckingthefrequencyandconsistencyofbowelmovementsRationale:TheprincipalmanifestationsofCrohn'sdiseasearediarrheaandabdominalpain.Infliximab(Remicade)is an immunomodulator thatreducesthedegreeofinflammationinthecolon,therebyreducingthediarrhea.Options1,3,and4areunrelatedtothismedication.3.AnepisodeofdiarrheaRationale:Loperamideisanantidiarrhealagent.Itisusedtomanageacuteandalsochronicdiarrheainconditionssuchasinflammatoryboweldisease.Loperamidealsocanbeusedtoreducethevolume ofdrainagefroman ileostomy. It is not usedfor theconditions inoptions1,2, and 4.4.Nausea andvomitingRationale:Ondansetronisanantiemeticusedtotreatpostoperativenauseaandvomiting,aswellasnauseaandvomitingassociatedwithchemotherapy.Theotheroptionsareincorrect.3.ReductionofsteatorrheaRationale:Pancrelipase(PancreaseMT)isapancreaticenzymeusedinclientswithpancreatitisas a digestive aid. The medication shouldreducetheamount offattystools(steatorrhea).Anotherintendedeffectcouldbeimprovednutritionalstatus.Itisnotusedtotreatabdominalpainorheartburn.Itsusecouldresultinweightgainbutshouldnotresultinweightlossifitisaidingindigestion.3.ConfusionRationale:Cimetidineisahistamine2(H2)-receptorantagonist.Olderclientsareespeciallysusceptibletocentralnervoussystemsideeffectsofcimetidine.Themostfrequentoftheseisconfusion.Lesscommoncentralnervoussystemsideeffectsincludeheadache,dizziness, drowsiness, andhallucinations.

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39.39.) The client with a gastric ulcer has a prescription forsucralfate (Carafate), 1 g by mouth four times daily. The nurseschedules the medication for which times?1.With meals and atbedtime2.Every 6hoursaround theclock3.Onehourafter meals and atbedtime4.Onehourbefore meals and atbedtime40.40.)Theclient who chronically uses nonsteroidal anti-inflammatorydrugshasbeentakingmisoprostol(Cytotec).Thenurse determines that the medication ishavingtheintendedtherapeuticeffectif which of the following isnoted?1.Resolveddiarrhea2.Reliefof epigastricpain3.Decreased plateletcount4.Decreased white blood cellcount41.41.)Theclienthasbeen takingomeprazole (Prilosec) for 4weeks.Theambulatorycarenurseevaluatesthattheclientisreceiving optimalintended effectof the medication if theclient reports the absence of whichsymptom?1.Diarrhea2.Heartburn3.Flatulence4.Constipation42.42.) A client with a peptic ulcer is diagnosed with aHelicobacter pylori infection.Thenurse is reinforcingteaching for the clientaboutthe medications prescribed,including clarithromycin(Biaxin),esomeprazole(Nexium),andamoxicillin(Amoxil).Whichstatementbytheclientindicatesthe best understanding of the medicationregimen?1."Myulcerwillhealbecausethesemedicationswillkillthebacteria."2."ThesemedicationsareonlytakenwhenIhavepainfrommyulcer."3."Themedicationswillkillthebacteriaandstoptheacidproduction."4."These medications will coat the ulcer and decrease theacid production in mystomach."43.43.)Ahistamine(H2)-receptorantagonistwillbeprescribedforaclient.ThenurseunderstandsthatwhichmedicationsareH2-receptor antagonists?Selectall thatapply.1.Nizatidine(Axid)2.Ranitidine(Zantac)3.Famotidine(Pepcid)4.Cimetidine(Tagamet)5.Esomeprazole(Nexium)6.Lansoprazole(Prevacid)4.OnehourbeforemealsandatbedtimeRationale:Sucralfateis a gastricprotectant.The medication should bescheduledforadministration1hourbeforemealsandatbedtime.Themedicationistimedtoallowittoformaprotectivecoatingover theulcerbeforefoodintake stimulates gastric acidproductionand mechanical irritation. Theotheroptionsareincorrect.2.ReliefofepigastricpainRationale:Theclientwhochronicallyusesnonsteroidalanti-inflammatorydrugs(NSAIDs)ispronetogastricmucosalinjury.Misoprostolisagastricprotectantand is given specificallytopreventthisoccurrence.Diarrheacanbeasideeffectofthemedication,butisnotanintendedeffect.Options3and4areincorrect.2.HeartburnRationale:Omeprazoleisaprotonpumpinhibitorclassifiedasanantiulceragent.Theintendedeffectofthemedicationisreliefofpainfromgastricirritation,oftencalledheartburnbyclients.Omeprazoleisnotusedtotreattheconditionsidentifiedinoptions1,3,and4.3."Themedicationswillkillthebacteriaandstoptheacidproduction."Rationale:TripletherapyforHelicobacterpyloriinfectionusuallyincludestwoantibacterialdrugsandaprotonpumpinhibitor.Clarithromycinandamoxicillinareantibacterials.Esomeprazoleisaprotonpumpinhibitor.Thesemedicationswillkillthebacteriaanddecreaseacidproduction.1.Nizatidine(Axid)2.Ranitidine(Zantac)3.Famotidine(Pepcid)4.Cimetidine (Tagamet)Rationale:H2-receptorantagonistssuppresssecretionof gastric acid,alleviate symptoms ofheartburn,andassistinpreventingcomplicationsofpepticulcerdisease.Thesemedicationsalsosuppressgastricacidsecretionsandareusedinactiveulcerdisease,erosiveesophagitis, and pathologicalhypersecretoryconditions. Theothermedications listedare protonpumpinhibitors.H2-receptorantagonistsmedicationnamesendwith-dine.Protonpumpinhibitorsmedicationnamesendwith-zole.

ATI Pharmacology Proctored Test Bank with Answers (313 Solved Questions) - Page 12 preview image

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44.44.) A client is receiving acetylcysteine(Mucomyst), 20% solution diluted in 0.9%normal saline by nebulizer.Thenurseshouldhavewhich itemavailablefor possibleuseafter giving this medication?1.Ambubag2.Intubationtray3.Nasogastrictube4.Suctionequipment45.45.) A clienthasa prescriptiontotakeguaifenesin(Humibid)every 4hours,asneeded.Thenursedeterminesthattheclientunderstands the most effectiveuseof thismedication if the client states thatheorshewill:1.Watch for irritability as asideeffect.2.Takethe tablet with a full glass ofwater.3.Takeanextradose if the cough isaccompanied byfever.4.Crushthesustained-releasetabletifimmediaterelief isneeded.46.46.) A postoperative client has received adose of naloxone hydrochloride forrespiratory depression shortly after transferto the nursing unit from the postanesthesiacare unit. After administration of themedication, the nurse checks the client for:1.Pupillarychanges2.Scatteredlungwheezes3.Sudden increase inpain4.Sudden episodes ofdiarrhea47.47.)Aclienthasbeentakingisoniazid(INH)for2 months.Theclient complainstoa nurseaboutnumbness,paresthesias,andtinglinginthe extremities.Thenurse interprets that theclient isexperiencing:1.Hypercalcemia2.Peripheralneuritis3.Small blood vesselspasm4.Impaired peripheralcirculation4. Suction equipmentRationale:Acetylcysteinecanbegivenorallyorbynasogastrictubetotreatacetaminophenoverdose,or it may be given by inhalationforuse as a mucolytic. The nurseadministeringthismedicationasamucolyticshouldhavesuctionequipmentavailable in casetheclient cannot managetoclearthe increasedvolume ofliquefiedsecretions.2.Takethetabletwithafullglassofwater.Rationale:Guaifenesinisanexpectorant.Itshouldbetakenwithafullglassofwatertodecreaseviscosityofsecretions.Sustained-releasepreparationsshouldnotbebrokenopen,crushed, orchewed.The medication may occasionally causedizziness,headache,ordrowsinessassideeffects.Theclientshouldcontactthehealthcareproviderifthecoughlastslongerthan1weekorisaccompaniedbyfever,rash,sorethroat,orpersistentheadache.3.SuddenincreaseinpainRationale:Naloxonehydrochlorideisanantidotetoopioidsandmayalsobegiventothepostoperativeclienttotreatrespiratorydepression.When givento thepostoperativeclientforrespiratorydepression,itmayalsoreversetheeffectsofanalgesics.Therefore,thenursemustchecktheclientforasuddenincreaseinthelevel of painexperienced.Options1,2, and 4arenot associated with thismedication.2.PeripheralneuritisRationale:AcommonsideeffectoftheTBdrugINHisperipheralneuritis.Thisismanifestedbynumbness,tingling,andparesthesiasintheextremities.Thissideeffectcanbeminimizedbypyridoxine(vitaminB6)intake.Options1,3,and4areincorrect.

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48.48.)Aclientistobegina6-monthcourseof therapy with isoniazid(INH). A nurse planstoteach theclientto:1.Drinkalcoholinsmallamountsonly.2.Report yelloweyesorskinimmediately.3.IncreaseintakeofSwissoragedcheeses.4.Avoidvitaminsupplementsduringtherapy.49.49.) A client has been started onlong-term therapy with rifampin(Rifadin). A nurse teaches theclient that themedication:1.Shouldalwaysbetakenwithfood orantacids2.Shouldbedouble-dosedifonedose isforgotten3.Causesorange discoloration ofsweat,tears,urine,andfeces4.Maybe discontinuedindependentlyifsymptomsaregone in 3months50.50.) A nursehasgiven a clienttaking ethambutol(Myambutol)informationaboutthemedication.Thenurse determines that theclientunderstandstheinstructionsif the client states thatheorshewill immediatelyreport:1.Impaired sense ofhearing2.Problems withvisualacuity3.Gastrointestinal(GI)sideeffects4.Orange-red discolorationofbodysecretions51.51.) Cycloserine (Seromycin) isadded to the medication regimenfor a client with tuberculosis.Which of the following would thenurse include in the client-teaching plan regarding thismedication?1.Totakethemedicationbeforemeals2.Toreturntotheclinicweeklyforserumdrug-leveltesting3.It is not necessarytocall thehealthcareprovider(HCP)ifaskinrashoccurs.4.It is not necessarytorestrictalcoholintake with thismedication.2.Reportyelloweyesorskinimmediately.Rationale:INHishepatotoxic,andthereforetheclientistaughttoreportsignsandsymptomsofhepatitisimmediately(whichincludeyellowskinandsclera).Forthesamereason,alcoholshouldbeavoidedduringtherapy.TheclientshouldavoidintakeofSwisscheese,fishsuchastuna,andfoodscontainingtyraminebecausetheymaycauseareactioncharacterizedbyrednessanditching oftheskin, flushing, sweating,tachycardia, headache,or lightheadedness. The clientcanavoiddevelopingperipheralneuritisbyincreasingtheintakeofpyridoxine(vitaminB6)duringthecourseofINHtherapyforTB.3.Causesorangediscolorationofsweat,tears,urine,andfecesRationale:Rifampin should betaken exactlyasdirectedas part of TBtherapy.Doses should not bedoubledorskipped.Theclientshouldnotstoptherapyuntildirectedtodosobyahealthcareprovider.The medication should beadministeredon anemptystomach unless it causesgastrointestinalupset,andthenitmaybetakenwithfood.Antacids,ifprescribed,shouldbetakenatleast1hourbeforethemedication.Rifampincausesorange-reddiscolorationofbodysecretionsandwillpermanentlystainsoftcontactlenses.2. Problems with visual acuityRationale:Ethambutolcausesopticneuritis,whichdecreasesvisualacuityandtheabilitytodiscriminatebetweenthecolorsredandgreen.Thisposesapotentialsafetyhazardwhenaclientisdrivingamotorvehicle.Theclientistaughttoreportthissymptomimmediately.TheclientisalsotaughttotakethemedicationwithfoodifGIupsetoccurs.Impairedhearingresultsfromantituberculartherapywithstreptomycin.Orange-reddiscolorationofsecretionsoccurswithrifampin(Rifadin).2.Toreturntotheclinicweeklyforserumdrug-leveltestingRationale:Cycloserine(Seromycin)isanantitubercularmedicationthatrequiresweeklyserumdrugleveldeterminationstomonitorforthepotentialofneurotoxicity.Serumdruglevelslowerthan30mcg/mLreducetheincidenceofneurotoxicity.Themedicationmustbetakenaftermealstopreventgastrointestinalirritation.TheclientmustbeinstructedtonotifytheHCPifaskinrashorsignsofcentralnervoussystemtoxicityarenoted.Alcoholmustbeavoidedbecauseitincreasestheriskofseizureactivity.

ATI Pharmacology Proctored Test Bank with Answers (313 Solved Questions) - Page 14 preview image

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52.52.) A client with tuberculosis is beingstarted on antituberculosis therapy withisoniazid (INH). Before giving the client thefirst dose, a nurse ensures that which of thefollowing baseline studies hasbeencompleted?1.Electrolytelevels2.Coagulationtimes3.Liverenzymelevels4.Serum creatininelevel53.53.)Rifabutin(Mycobutin)isprescribedforaclient with active Mycobacteriumaviumcomplex(MAC)disease and tuberculosis.Thenurse monitors for whichsideeffectsof themedication?Selectall thatapply.1.Signs ofhepatitis2.Flu-likesyndrome3.Low neutrophilcount4.Vitamin B6 deficiency5.Ocularpainor blurredvision6.Tingling and numbness of thefingers54.54.)Anursereinforcesdischargeinstructionstoa postoperative client who is takingwarfarin sodium (Coumadin).Whichstatement,ifmadebytheclient,reflectstheneedfor furtherteaching?1."Iwilltakemypillseverydayatthesametime."2."Iwillbecertaintoavoidalcoholconsumption."3."Ihavealready called my familytopickupa Medic-Alertbracelet."4."IwilltakeEcotrin(enteric-coatedaspirin)formyheadachesbecauseitiscoated."55.55.) A client who is receivingdigoxin(Lanoxin) dailyhasa serumpotassiumlevelof3.0mEq/Landiscomplainingofanorexia.Ahealthcareproviderprescribesadigoxinleveltorule out digoxintoxicity. A nursecheckstheresults,knowingthatwhichofthefollowing is the therapeutic serum level(range)fordigoxin?1.3to5ng/mL2.0.5to2ng/mL3.1.2 to2.8ng/mL4. 3.5to5.5ng/mL3.Liver enzymelevelsRationale:INHtherapycan cause an elevation ofhepaticenzyme levels and hepatitis.Therefore,liverenzymelevelsaremonitoredwhentherapyisinitiatedandduringthefirst3monthsoftherapy.Theymaybemonitoredlongerintheclientwhoisgreaterthan age50or abusesalcohol.1.Signs ofhepatitis2.Flu-likesyndrome3.Lowneutrophilcount5.OcularpainorblurredvisionRationale:Rifabutin(Mycobutin)maybeprescribedforaclientwithactiveMACdiseaseandtuberculosis. It inhibits mycobacterialDNA-dependentRNA polymerase andsuppressesproteinsynthesis.Sideeffectsincluderash,gastrointestinaldisturbances,neutropenia(lowneutrophilcount),red-orangebodysecretions,uveitis(blurredvisionandeyepain),myositis,arthralgia,hepatitis,chestpainwithdyspnea,andflu-likesyndrome.VitaminB6deficiencyandnumbnessandtinglingintheextremitiesareassociatedwiththeuseofisoniazid(INH).Ethambutol(Myambutol)alsocausesperipheralneuritis.4."IwilltakeEcotrin(enteric-coatedaspirin)formyheadachesbecauseitiscoated."Rationale:Ecotrin is an aspirin-containingproductand should be avoided. Alcoholconsumption should be avoided by a clienttakingwarfarin sodium.Takingprescribedmedicationatthesametimeeachdayincreasesclientcompliance.TheMedic-Alertbraceletprovideshealthcarepersonnelemergencyinformation.2.)0.5to2ng/mLRationale:Therapeuticlevelsfordigoxinrangefrom0.5to2ng/mL.Therefore,options1,3,and 4areincorrect.

ATI Pharmacology Proctored Test Bank with Answers (313 Solved Questions) - Page 15 preview image

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56.56.)Heparinsodiumisprescribedfortheclient.Thenurseexpectsthatthehealthcareproviderwillprescribewhichofthefollowingtomonitor for a therapeuticeffectof themedication?1.Hematocritlevel2.Hemoglobinlevel3.Prothrombintime(PT)4.Activatedpartialthromboplastintime(aPTT)57.57.)A nurse is monitoring a client who istaking propranolol (Inderal LA). Whichdatacollectionfindingwouldindicateapotentialseriouscomplication associatedwithpropranolol?1.Thedevelopmentofcomplaintsofinsomnia2.Thedevelopmentofaudibleexpiratorywheezes3.A baseline bloodpressureof 150/80mmHgfollowedbyabloodpressureof138/72 mm Hg aftertwodoses of themedication4.A baseline restingheartrate of88beats/minfollowed by a restingheartrate of 72beats/minaftertwodosesofthemedication58.58.) Isosorbide mononitrate (Imdur) isprescribed for a client with anginapectoris. The client tells the nurse thatthe medication is causing a chronicheadache. The nurse appropriatelysuggests that the client:1.Cutthe dose inhalf.2.Discontinue themedication.3.Takethe medication withfood.4.Contact the health care provider(HCP).59.59.) A client is diagnosed with anacutemyocardial infarction and is receivingtissue plasminogen activator, alteplase(Activase, tPA). Which action is a prioritynursing intervention?1.Monitor for renalfailure.2.Monitor psychosocialstatus.3.Monitor for signs ofbleeding.4.Haveheparinsodiumavailable.4.Activatedpartialthromboplastintime(aPTT)Rationale:ThePTwillassessforthetherapeuticeffectofwarfarinsodium(Coumadin)andtheaPTTwillassessthetherapeuticeffectofheparinsodium.Heparinsodiumdosesaredeterminedbasedontheselaboratoryresults.Thehemoglobinandhematocritvaluesassessredblood cellconcentrations.2.ThedevelopmentofaudibleexpiratorywheezesRationale:Audibleexpiratorywheezesmayindicateaseriousadversereaction,bronchospasm.β-Blockers may induce thisreaction,particularly in clients withchronicobstructivepulmonarydiseaseorasthma.Normaldecreasesinbloodpressureandheartrateareexpected.Insomniaisafrequentmildsideeffectandshouldbemonitored.3.Takethemedicationwithfood.Rationale:Isosorbidemononitrateisanantianginalmedication.Headacheisafrequentsideeffectof isosorbidemononitrateand usually disappears duringcontinuedtherapy.If aheadacheoccursduringtherapy,theclientshouldbeinstructedtotakethemedicationwithfoodormeals.ItisnotnecessarytocontacttheHCPunlesstheheadachespersistwiththerapy.Itisnotappropriatetoinstructtheclienttodiscontinuetherapyoradjustthedosages.3.Monitorforsignsofbleeding.Rationale:Tissueplasminogenactivatorisathrombolytic.Hemorrhageisacomplicationofanytypeofthrombolyticmedication.Theclientismonitoredforbleeding.Monitoringforrenalfailureandmonitoringtheclient'spsychosocialstatusareimportantbutarenotthemostcriticalinterventions.Heparinisgivenafterthrombolytictherapy,butthequestionisnotaskingaboutfollow-upmedications.

ATI Pharmacology Proctored Test Bank with Answers (313 Solved Questions) - Page 16 preview image

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60.60.) A nurse is planningtoadministerhydrochlorothiazide(HydroDIURIL)toaclient.Thenurse understands that which ofthe followingareconcerns relatedtotheadministration of this medication?1.Hypouricemia,hyperkalemia2.Increasedriskofosteoporosis3.Hypokalemia, hyperglycemia, sulfaallergy4.Hyperkalemia, hypoglycemia, penicillinallergy61.61.)Ahomehealth care nurse is visitingaclient with elevated triglyceride levels andaserumcholesterollevelof398mg/dL.Theclient is taking cholestyramine (Questran).Which of the following statements, ifmadebytheclient,indicatestheneedforfurthereducation?1."Constipation and bloatingmightbe aproblem."2."I'llcontinuetowatchmydietandreducemyfats."3."Walkinga mile eachdaywill help thewholeprocess."4."I'llcontinuemynicotinicacidfromthehealth foodstore."62.62.)Aclientisonnicotinicacid(niacin)forhyperlipidemia and the nurse providesinstructionstothe clientaboutthemedication.Whichstatementbytheclientwould indicate an understanding of theinstructions?1."It is not necessarytoavoidtheuseofalcohol."2."Themedicationshouldbe taken withmealstodecreaseflushing."3."Clay-colored stoolsarea commonsideeffectandshouldnot be ofconcern."4."Ibuprofen (Motrin) taken30minutesbefore the nicotinic acidshoulddecreasetheflushing."3.Hypokalemia,hyperglycemia,sulfaallergyRationale:Thiazidediureticssuchashydrochlorothiazidearesulfa-basedmedications,andaclientwithasulfaallergyisatriskforanallergicreaction.Also,clientsareatriskforhypokalemia,hyperglycemia,hypercalcemia,hyperlipidemia,andhyperuricemia.4."I'llcontinuemynicotinicacidfromthehealthfoodstore."Rationale:Nicotinicacid,evenanover-the-counterform,shouldbeavoidedbecauseitmayleadtoliver abnormalities. All lipid-lowering medications also can cause liverabnormalities,soacombinationofnicotinicacidandcholestyramineresinistobeavoided.Constipationandbloatingarethetwomostcommonsideeffects.Walkingandthereductionoffatsinthedietaretherapeuticmeasurestoreducecholesteroland triglyceridelevels.4."Ibuprofen(Motrin)taken30minutesbeforethenicotinicacidshoulddecreasetheflushing."Rationale:Flushing is a sideeffectof this medication. Aspirin or anonsteroidalanti-inflammatorydrugcanbetaken30minutesbeforetakingthemedicationtodecreaseflushing.Alcoholconsumptionneedstobeavoidedbecauseitwillenhancethissideeffect.Themedicationshouldbetakenwithmeals,thiswilldecreasegastrointestinalupset.Takingthemedicationwithmealshasnoeffectontheflushing.Clay-coloredstoolsareasignofhepaticdysfunctionandshouldbeimmediatelyreportedtothehealthcare provider(HCP).

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