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Nursing 552: Practice Exam 3 with Answers (45 Solved Questions)

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    Nursing 552: Exam 3 Practice Questions 1. Which statement by a patient should alert you to a serious issue related to the patient's use of Atorvastatin? A) "I've been feeling really down lately." B) "My urine has been a lot darker than usual." C) "I've been having issues with blurry vision lately" D) "My heart feels like it beats really fast sometimes." Answer: B. Rhabdomylosis is a rare but serious side effect of statin medications. Reference: Chapter 39 2. An 66 year old male has been taking Simvas- tatin for three years. The Nurse Practitioner should be concerned about which new med- ication prescribed for this patient in combina- tion with Simvastatin: A) Metoprolol B) Multivitamin C) Azithromycin D) Tylenol Answer: C. Antitbiotics, specifically macrolide an- tibiotics put elderly patients at high risk for muscle toxi- city when mixed with statin medications. Reference: Chapter 39 3. Which medication is absolutely contraindicat- ed for a new 23 year old pregnant patient who presents with hyperlipidemia not responsive to lifestyle modifications? A) Rosuvastatin B) Nicotinic Acid C) Fenofibrate D) Gemfibrozil Answer: A. Statins are pregnancy category X. Reference: Chapter 39 4. Which drug to treat hyperlipidemia acts by inhibiting the mobilization of free fatty acids (FFA) from peripheral adipose tissue to the liver? A) Statins B) Fibric Acids C) Niacin (Nicotinic Acid) D) Bile acid-binding Resins E) Ezetimibe Answer: C. The mobilization of FFA from peripheral adipose tis- sue to the liver is inhib- ited by nicotinic acid. The conversion of VLDL to LDL is decreased as a conse- quence of this decrease or an additional hepatic ef- 1 / 11

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    Nursing 552: Exam 3 Practice Questions fect via nicotinic acid and the synthesis and secre- tion of VLDLs are reduced. Although the mechanism is unknown, nicotinic acid also increases serum HDL cholesterol concentrations by up to 30%. Question from: https://www.pro- profs.com/quiz-school/quizshow tle=pharm-exam-3-antihy- perlipidemics&q=19 5. Which antihyperlipidemic is most effective when given in combination with other drugs? A. Niacin B. Bile acid-binding resins C. Ezetimibe D. Statins E. Fibric Acid Answer: A. If a bile acid-binding resin is added, 40-60% reduction in LDL. In triple therapy with bile acid-binding resin plus a statin, it decreases LDL by 70% or more. Question from: https://www.pro- profs.com/quiz-school/quizshow tle=pharm-exam-3-antihy- perlipidemics&q=19 6. How can you avoid some of the adverse ef- fects seen with Niacin (dyspepsia, skin flush- ing, itching)? A) By taking an NSAID like Aspirin concur- rently. B) By taking the medication at night. C) By taking the medication with food. D) By taking the medication on an empty Answer: A. Question from: https://www.pro- profs.com/quiz-school/quizshow tle=pharm-exam-3-antihy- perlipidemics&q=19 2 / 11

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    Nursing 552: Exam 3 Practice Questions stomach. E) The Adverse affects cannot be avoided. 7. What conditions are worsened with Niacin (nicotinic acid)? A) Gout B) Cardiac atrial arrhythmias C) Diabetes D) Gallbladder disease E) All of the above Answer: E. Gout - see an increase in uric acid because it com- petes for excretion - Dia- betes - glucose levels are affected - Gallbladder Dis- ease - releases bile acids. Question from: https://www.pro- profs.com/quiz-school/quizshow tle=pharm-exam-3-antihy- perlipidemics&q=19 8. Giving Niacin in combination with statins causes an increased risk of what disease? A) Gout. B) MI. C) Renal disease. D) Myopathy (rhabdomyolysis) E) Hepatic Failure Answer: D. Question from: https://www.pro- profs.com/quiz-school/quizshow tle=pharm-exam-3-antihy- perlipidemics&q=19 9. What are the two drugs that are classified as fibric acid derivatives? A) Niacin and Gemfibrozil. B) Gemfibrozil and Fenofibrate. C) Fenofibrate and Ezetimibie. D) Simvastatin and Gemfibrozil. Answer: B. Question from: https://www.pro- profs.com/quiz-school/quizshow tle=pharm-exam-3-antihy- perlipidemics&q=19 10. What do the fibric acid derivatives do? A) Enhance oxidation of FA in liver and mus- cle. B) Reduce rate of lipogenesis in the liver. Answer: D. Question from: https://www.pro- profs.com/quiz-school/quizshow 3 / 11

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