Test Bank NeuroscienceChapter 6by Laurie Lundy-EkmanWhat is an example of Calcium ion acting as a second messenger?--answer-IP3 causing organelles to discharge their calcium stores-increase in cytosolic calcium can trigger widespread and long lastingeffects-one of these effects could be activation of CaMK ( calcium-calmodulin-dependent protein kinase)-CaMK is important in the molecular mechanisms of memoryWhat occurs whenG protein activates phospholipases C?--answer--PLCacts on the membrane phospholipid PIP2 by splitting it into two-PIP2 becomes DAG and IP3-DAG stays on one plane and activates downstream enzyme proteinkinase C (PKC)-IP3 diffuses away from the membrane and causes organelles todischarge their calcium storesWhat is the antagonist for AMPA glutamate receptors?--answer-CNQXWhat is the antagonist for NMDA glutamate receptors?--answer-AP5What is the difference between NMDA and AMPA glutamate receptors?--answer-slight differences in the protein that makes up the recptorDiverging neurotransmitter effects are represented by--answer-themultitude of consequences a single neurotransmittermay have because itaffects many different receptor subtypes in postsynaptic neurons-This effect may occur in a single neuron that possesses G-protein-coupled receptors with two or more intracellular functions or, potentially,single neurons that elaborate different types of receptors in differentparts of the neuronPreview Mode
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