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2024-2025 Anemias Disorders (PEARLS) (Smarty PANCE) with Answers (73 Solved Questions)

Get ahead with 2024-2025 Anemias Disorders, featuring real exam questions for better preparation.

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Anemias(PEARLS)-SmartyPANCE100% VERIFIEDANSWERS 2024/2025Normal or ↓ MCV, ↓ TIBC, ↑ Ferritin (high iron stores) ↓ serum erythropoietinAnemia of chronic diseaseThe only anemia where all three cell lines are decreased(pancytopenia)↓ WBC, ↓RBC, ↓ Platelets-will have normal MCV and ↓ ReticAplastic anemia↓ Folate,↑ MCV (macrocytic anemia)looks like B12 butno neurologic symptoms.Common in alcoholicsFolate deficiencyAfter infection or medication in an African American male +Heinz Bodies and BiteCells on smear. Flare triggers: Fava beans, antimalarials, sulfonamidesG6PD deficiencyHistory of jaundice, transfusion, new medication or infection(+) direct coombstestAutoimmune Hemolytic anemia↓ MCV (microcytic), ↑ TIBC, ↓ Ferritin (low iron stores) ↓ MCH (hypochromic).Associated withpicaand nail spooning, target cellsIron deficiency

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African American, pain, family history of blood disorder.Hemoglobinelectrophoresis: Hemoglobin S, Blood smear: Sickled RBCs, howell-Jolly bodies,target cellsSickle cell anemiaMicrocytic hypochromic, elevated iron. Most severe, Mediterranean descent,failure to thrive. Hemoglobin electrophoresis: Hemoglobin A2 and F.Beta thalassemia majorMicrocytic hypochromic, elevated iron. Mild anemia, often misdiagnosed as irondeficient. Hemoglobin electrophoresis:Hemoglobin A2Beta thalassemia traitChinese and southeast Asians. Hemoglobin electrophoresis: Hemoglobin H (Hdisease), Hemoglobin Bart's (hydrops fetalis), Hemoglobin A (trait)Alpha thalassemia↑ MCV (macrocytic anemia),Hypersegmented Neutrophilsand normalfolate,decreased vibratory andposition senseVitamin B12 deficiencyLess than 10% radiolabeled vitamin B12 in urine. Normal results when repeatedwith administration of intrinsic factorSchilling testfor the diagnosis ofpernicious anemia (antibody to intrinsic factor)What disorderis a hemoglobin electrophoresis result of "SS" indicative of?Sickle cell diseaseWhat disorder is a hemoglobin electrophoresis result of "SA" indicative of?
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Physician Assistant National Certifying Exam

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