USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020)

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 1 preview image

Loading page ...

USMLE®Step 1Lecture Notes2020USMLE®is a joint program of the Federation of State Medical Boards (FSMB) and the NationalBoard of Medical Examiners (NBME), which neither sponsor nor endorse this product.AnatomyBehavioral Scienceand Social SciencesBiochemistry andMedical GeneticsImmunology andMicrobiologyPathologyPharmacologyPhysiology

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 2 preview image

Loading page ...

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 3 preview image

Loading page ...

USMLE® is a joint program of The Federation of State Medical Boards of the United States, Inc.and the National Board of Medical Examiners.USMLE®Step 1Lecture Notes2020

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 4 preview image

Loading page ...

Copyright © 2020Kaplan, Inc.ISBN:978-1-5062-5497-5All rights reserved. The text of this publication, or any part thereof, may not be reproduced in any manner whatsoever withoutwritten permission from the publisher. This book may not be duplicated or resold, pursuant to the terms of your KaplanEnrollment Agreement.USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners(NBME), which neither sponsor nor endorse this product.

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 5 preview image

Loading page ...

USMLETM*STEP 1ANATOMYUSMLETM*STEP 1BEHAVIORAL SCIENCEUSMLETM*STEP 1BIOCHEMISTRY AND MEDICAL GENETICSUSMLETM*STEP 1IMMUNOLOGY AND MICROBIOLOGYUSMLETM*STEP 1PATHOLOGYUSMLETM*STEP 1PHARMACOLOGYUSMLETM*STEP 1PHYSIOLOGY

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 6 preview image

Loading page ...

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 7 preview image

Loading page ...

USMLE®Step 1Lecture Notes2020Anatomy00_Anatomy_FM.indd128/08/1910:17 PM

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 8 preview image

Loading page ...

USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and the National Boardof Medical Examiners (NBME), which neither sponsor nor endorse this product.This publication is designed to provide accurate information in regard to the subject matter coveredas of its publication date, with the understanding that knowledge and best practice constantly evolve.The publisher is not engaged in rendering medical, legal, accounting, or other professional service. Ifmedical or legal advice or other expert assistance is required, the services of a competent professionalshould be sought. This publication is not intended for use in clinical practice or the delivery of medi-cal care. To the fullest extent of the law, neither the Publisher nor the Editors assume any liability forany injury and/or damage to persons or property arising out of or related to any use of the materialcontained in this book.© 2020 by Kaplan, Inc.Published by Kaplan Medical, a division of Kaplan, Inc.750 Third AvenueNew York, NY 1001710 9 8 7 6 5 4 3 2 1All rights reserved. The text of this publication, or any part thereof, may not be reproduced in anymanner whatsoever without written permission from the publisher.Course ISBN: 978-1-5062-5469-2This book may not be duplicated or resold, pursuant to the terms of your Kaplan EnrollmentAgreement.Retail ISBN: 978-1-5062-5467-8Kaplan Publishing print books are available at special quantity discounts to use for sales promotions,employee premiums, or educational purposes. For more information or to purchase books, please callthe Simon & Schuster special sales department at 866-506-1949.00_Anatomy_FM.indd228/08/1910:17 PM

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 9 preview image

Loading page ...

EditorsJames White, PhDAssistant Professor of Cell BiologySchool of Osteopathic MedicineRowan UniversityStratford, NJAdjunct Assistant Professor of Cell and Developmental BiologyUniversity of Pennsylvania School of MedicinePhiladelphia, PADavid Seiden, PhDProfessor of Neuroscience and Cell BiologyRutgers–Robert Wood Johnson Medical SchoolPiscataway, NJ00_Anatomy_FM.indd328/08/1910:17 PM

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 10 preview image

Loading page ...

We want to hear what you think. What do you like or not like about the Notes?Please email us atmedfeedback@kaplan.com.00_Anatomy_FM.indd428/08/1910:17 PM

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 11 preview image

Loading page ...

vTable of ContentsPart I: Early Embryology and Histology: EpitheliaChapter 1:Gonad Development 3Chapter 2:First 8 Weeks of Development 7Chapter 3:Histology: Epithelia 13Part II: Gross AnatomyChapter 1:Back and Autonomic Nervous System 21Chapter 2:Thorax 35Chapter 3:Abdomen, Pelvis, and Perineum 85Chapter 4:Upper Limb 179Chapter 5:Lower Limb 195Chapter 6:Head and Neck 207Part III: NeuroscienceChapter 1:Nervous System Organization and Development 225Chapter 2:Histology of the Nervous System 235Chapter 3:Ventricular System 245Chapter 4:The Spinal Cord 251Chapter 5:The Brain Stem 275Chapter 6:The Cerebellum 309Chapter 7:Basal Ganglia 31700_Anatomy_FM.indd528/08/1910:17 PM

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 12 preview image

Loading page ...

viChapter 8:Visual Pathways 325Chapter 9:Diencephalon 335Chapter 10:Cerebral Cortex 341Chapter 11:Limbic System 359Index 365Additional resources available atwww.kaptest.com/usmlebookresources00_Anatomy_FM.indd628/08/1910:17 PM

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 13 preview image

Loading page ...

PART IEarly Embryology andHistology: Epithelia01_Chapter_1.indd18/3/1812:20 PM

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 14 preview image

Loading page ...

01_Chapter_1.indd28/3/1812:20 PM

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 15 preview image

Loading page ...

3Learning Objectives❏Explain information related to indifferent gonad❏Interpret scenarios on testis and ovary❏Answer questions about meiosis❏Interpret scenarios on spermatogenesis❏Solve problems concerning oogenesisGONAD DEVELOPMENTAlthough sex is determined at fertilization, the gonads initially go throughanindifferent stageweeks 4–7 when there are no specific ovarian or tes-ticular characteristics. The indifferent gonads develop in a longitudinalelevation orridge ofintermediate mesodermcalled theurogenital ridge.The components of the indifferent gonads are as follows:•Primordial germ cellsprovide a critical inductive influence ongonad development, migrating in at week 4. They arise from thelining cells in the wall of the yolk sac.•Primary sex cordsare finger-like extensions of the surface epithe-lium which grow into the gonad that are populated by the migrat-ing primordial germ cells.•Mesonephric (Wolffian)and theparamesonephric (Mullerian)ducts of the indifferent gonad contribute to the male and femalegenital tracts, respectively.The indifferent gonads develop into either thetestis or ovary.Development of thetestisandmale reproductive systemis directed by thefollowing:•Sry geneon the short arm of theY chromosome, which encodesfortestis-determining factor(TDF)•Testosterone,which is secreted by theLeydig cells•Müllerian-inhibiting factor (MIF),which is secreted by theSertolicells•Dihydrotestosterone (DHT):external genitaliaDevelopment of theovaryandfemale reproductive systemrequires estro-gen. Ovarian development occurs in the absence of the Sry gene and in thepresence of the WNT4 gene.Gonad Development101_Chapter_1.indd38/3/1812:20 PM

USMLE Step 1 Lecture Notes 2020: 7-Book Set, 1st Edition (2020) - Page 16 preview image

Loading page ...

4Part IlEarly Embryology and Histology: EpitheliaAnatomyPharmacologyPhysiologyPathologyMicrobiologyImmunologyBiochemistryMedical GeneticsBehavioral Science/Social SciencesUrogenital ridgeYolk sacPrimordialgerm cellsMesonephric duct (Wolffian)Paramesonephric duct(Müllerian)Indifferent gonadTDFTestosteroneMIFNo factorsTestisand malegenital systemOvaryand femalegenital systemFigure I-1-1.Development of Testis and OvaryMIF: Müllerian-inhibiting factorTDF: testis-determining factorFigure I-1-1.Development of Testis and OvaryGAMETOGENESISMeiosisMeiosis, occurring within the testis and ovary, is a specialized process of celldivision that produces the male gamete(spermatogenesis)and female gamete(oogenesis).Therearenotabledifferencesbetweenspermatogenesisandoogenesis.Two cell divisions take place in meiosis. Inmeiosis I,the following events occur:•Synapsis:pairing of 46 homologous chromosomes•Crossing over:exchange of segments of DNA•Disjunction:separation of 46 homologous chromosome pairs(no centromere-splitting) into 2 daughter cells, each containing23 chromosome pairsInmeiosis II,synapsis does not occur, nor does crossing over. Disjunction doesoccur with centromere-splitting.MIF: Müllerian-inhibiting factorTDF: testis-determining factor01_Chapter_1.indd48/3/1812:20 PM

Study Now!

Document Details

Related Documents

USMLE Step 1 Lecture Notes 2020: Behavioral Science and Social Sciences (2020)

Master The Boards Usmle, Step 3 (2020)

USMLE Step 2 CK Lecture Notes 2020: Internal Medicine (2019)

USMLE Step 2 CK Lecture Notes 2019: Pediatrics (2019)

Master the Boards USMLE Step 2 CK, 6th Edition (2021)

Master the Boards USMLE Step 3 Edition: 7 (2022)

USMLE Step 2 CK Lecture Notes 2021: Internal Medicine, 1st Edition (2020)

First Aid for the USMLE Step 1 2024: A Student-to-Student Guide (2024)

Master the Boards USMLE Step 2 CK (2021)

USMLE Step 2 CK Lecture Notes 2021: Pediatrics (2020)

Company

Explore

Study Tools