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2024-2025 MN553 Advanced Pharmacology Final Exam with Answers (94 Solved Questions)

2024-2025 MN553 Advanced Pharmacology Final Exam with Answers helps you build confidence by practicing with past papers.

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MN553AdvancedPharmacologyFinalExam2024/2025 UPDATEVERIFIED ANSWERS4/4pointsJimisbeingtreatedforhypertension.Becausehehasahistoryofheartattack,thedrugchosenisatenolol.Betablockerstreathypertensionby:Questionoptions:artratetoimprovecardiacoutputcular smooth muscle toneosterone-mediated volumeactivityeoushumorproductionOpiatesareusedmainlytotreatmoderatetoseverepain.WhichofthefollowingisNOTtrueaboutthesedrugs?Questionoptions:escheduleddrugswhichrequireaDEAforthecontrolofpain.dverseeffectsofopiates are related to mu receptorstimulation. n antagonist to opiates.Whenconsideringwhichcholesterol-loweringdrugtoprescribe,whichfactordeterminesthetypeandintensityoftreatment?Questionoptions:ydiseaserisklevelholesterolBeingcompetentintheuseofinformationtechnologyinclinicalpracticeisexpectedinprofessionalnurses.Advancedpracticecompetenceincludestheabilityto:Questionoptions:ormationusingthemostcommonsearchengineslicensetoprescribe.lateonlymureceptorsentexpertsindeveloping,implementing,andevaluatinginformationSystems

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mstoassuretheintegrityofhealthinformationon technology to prescribe drugsTheNewYorkHeartAssociationandtheCanadianCardiovascularSocietyhavedescribedgradingcriteriaforlevelsofangina.Anginathatoccurswithunusuallystrenuousactivityoronwalkingorclimbingstairaftermealsisclass:Questionoptions:AnInvestigationalNewDrugisfiledwiththeU.S.FoodandDrugAdministration:Questionoptions:nufacturerhascompletedphaseIIItrialsrugisdiscoveredltestingofanynewdrug entity n testing ofany new drug entityTruecontraindicationstodiphtheria,tetanus,andacellularpertussis(DTaPorTdap)vaccineinclude:Questionoptions:04oF(40.5oC)afterpreviousDTaPvaccine y of seizures after DTaPvaccineegnancyeactionwithapreviousdose

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narrowtherapeuticrangegivenorallymaynotstayintheGItractlongenoughtoproduceanaction.AprovidermayconsidertestingforCYP2D6variantspriortostartingtamoxifenforbreastcancerto:Questionoptions:ientwillnothaveincreasedadversedrugreactionstothetamoxifential drug-drug interactions that may occur with tamoxifenmetabolizersoftamoxifenSeveralclassesofdrugshaveinteractionswithcholinergicblockers.Whichofthefollowingistrueabouttheseinteractions?Questionoptions:muscarinic effects may occur with antihistamines.blockersmaydecreasethesedativeeffectsofhypnotics.blockers are contraindicated with antipsychotics.Absolutecontraindicationsthatcliniciansmustconsiderwheninitiatingestrogentherapyinclude:Questionoptions:ddysfunctionaluterinebleedingarterialthromboemboliwithintheprioryearisoveFirst-linetherapyfortreatingtopicalfungalinfectionssuchastineacorporis(ringworm)ortineapedis(athlete’sfoot)wouldbe:Questionoptions:ineulvinazole(clotrimazole,miconazole)microsizeamkelihoodoftherapeuticfailurewithtamoxifentreatment.

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erhalf-lifeandwithdrawalsyndromehasafasteronsetwithouttaper.gesthalf-orointmentPreventativetherapyforclusterheadachesincludes:Questionoptions:elaxation therapynightlybeforebedocainefourtimesadayduring“clusters”ofheadachesInderal) dailyWhyistheconsistencyoftakingparoxetine(Paxil)andneverrunningoutofmedicationmoreimportantthanwithmostotherselectiveserotoninreuptakeinhibitors(SSRIs)?Questionoptions:life and the withdrawal syndrome has a faster onset. dictive in thedopaminergicrewardsystem.activatingofSSRImedicationsandwillcausethe person to have sudden deep sadness.Sookhasbeenprescribedgabapentintotreatneuropathicpainandiscomplainingoffeelingdepressedandhaving“strange”thoughts.Theappropriateinitialactionwouldbe:Questionoptions:doseuicidalideationthemedicationimmediatelydoseto half then slowly titrate up thedoseThedrugofchoicefortype2diabeticsismetformin.

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Metformin:Questionoptions:ycogenolysisbytheliverreleaseofinsulinfrombetacellsestinal uptake of glucoseghtgainassociatedwithhyperglycemiaGenderdifferencesbetweenmenandwomeninpharmacokineticsinclude:Questionoptions:astricemptyingsothatdrugsabsorbedinthestomachhavelessexposuretoabsorptionsitesortion of body fat so that lipophilic drugs have relatively greater volumes of distributionvels of bile acids so that drugs metabolized in the intestine have higher concentrationsnbloodflowratessodrugstendtotakelongertobeexcretedLisaisahealthynonpregnantadultwomanwhorecentlyhadaurinarytractinfection(UTI).SheisaskingaboutdrinkingcranberryjuicetopreventarecurrenceoftheUTI.Thecorrectanswertogiveherwouldbe:Questionoptions:esperdayofcranberryjuicecocktailwillprevent UTIs. rry juice or cranberry juiceextract may decrease UTIs in somepatients.videncethatcranberryjuicehelpsprevent UTIs. ice only works to preventUTIs in children.ACEinhibitorsarecontraindicatedinpregnancy.Whiletreatmentofheartfailureduringpregnancyisbestdonebyaspecialist,whichofthefollowingdrugclassesisconsideredtobesafe,atleastinthelaterpartsofpregnancy?Questionoptions:Whichofthefollowingholdstrueforthepharmacokineticsofwomen?Questionoptions:s

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yingisfasterthanthatofmen.flowisthesameasthat of men. strong concerning renal differences inelimination. that involve binding globulins areLarryistakingallopurinoltopreventgout.Monitoringofapatientwhoistakingallopurinolincludes:Questionoptions:oodcountine,andcreatinineclearanceseoteinThemostcost-effectivetreatmentfortwoorthreeimpetigolesionsonthefaceis:Questionoptions:(Altabax)ointmentdamycin solutionllin/clavulanate(Augmentin)Whichofthefollowingstatementsistrueaboutacutepain?Questionoptions:comesfrombodysurfacesandisonlysharpandwell-localized.n comes from the internal organs and is most responsive toimpactedbyestrogenlevels.acetaminophenandopiates.nispresentinadistantsiteforthentment

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painsourceandisbasedonactivationofthesamespinalsegmentas the actual pain site. pathic pain is caused by lack of bloodsupply to the nerves in a given area.Alaboratoryresultindicatesthatthepeaklevelforadrugisabovetheminimumtoxicconcentration.Thismeansthatthe:Questionoptions:nwillproducetherapeuticadverseresponsendosesmustbeshortenedactionofthedrug is too longWhileontestosteronereplacement,hemoglobinandhematocritlevelsshouldbemonitored.Levelssuggestiveofexcessiveerythrocytosisorabuseare:Questionoptions:14g/dlorhematocrit39%11.5g/dlorhematocrit31% 13 g/dl orhematocrit38%Awomanwhoispregnantandhashyperthyroidismisbestmanagedbyaspecialtyteamwhowillmostlikelytreatherwith:Questionoptions:acil(PTU)iodineatmentisbestdelayeduntil after her pregnancy endseffectsnwillproducean17.5g/dlorhematocrit54%

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th3first-orsecond-degreeLeonardiscompletinga6-monthregimentotreattuberculosis(TB).MonitoringofapatientonTBtherapyincludes:Questionoptions:tumcultures stx-raypyevery3monthsovePrecautionsthatshouldbetakenwhenprescribingcontrolledsubstancesinclude:Questionoptions:rescriptionforaScheduleIIdrugdirectlytothepharmacypre-signedprescriptionpadsinalockeddrawerintheclinicumbers to indicate the amount of drug to be prescribedPatientswhoareprescribedexogenousandrogensneedtobewarnedthatdecreasedlibido:Questionoptions:lsideeffectofandrogensandshouldbereportedtotheproviderhincreaseddosesofandrogens,sothepatientshouldlettheproviderknowifheishavingproblems n of early prostate cancer and he should make an appointment for a prostatescreening examWhichthefollowingpersonsshouldnothaveastatinmedicationordered?Questionoptions:familymemberswithhistoryof muscle issues whenstarted on statins th highlipids, but low BMI salwomanwithrecenthistoryofhysterectomy male withknown metabolic syndromer-proofpaperforallprescriptionswrittenforcontrolleddrugsithandrogentherapy
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