Microbiology - Diseases of the Skin and Eyes

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Study GuideMicrobiologyDiseases of the Skin and Eyes1.Fungal and Parasitic Skin DiseasesThe skin can be infected byfungiandparasites, leading to a variety of conditions. These infectionsoften causeitching, redness, swelling, or lesions, and they spread in different ways.1.1Athlete’s Foot and Ringworm (Dermatomycoses)Athlete’s footandringwormare common fungal skin infections caused by fungi from the generaTrichophyton,Microsporum, andEpidermophyton. These fungi are calleddermatophytes, and thediseases they cause are known asdermatomycoses.Infection spreads throughfragments of fungal hyphaeFluid-filled skin lesionsare commonSpread easily by contact with contaminated surfaces or skinTypesAthlete’s foottinea pedisRingworm of the bodytinea corporisRingworm of the grointinea crurisRingworm of the scalptinea capitisTreatment usually involvesantifungal ointments, and in more serious cases, the prescription druggriseofulvin.1.2SporotrichosisSporotrichosisis a fungal infection caused bySporothrix schenckii.Enters the body throughskin woundsCommonly associated withrose or barberry thornsandsphagnum mossBegins as anodular massat the site of entry

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Study GuideSpreads alonglymphatic vesselsCauses swelling (edema) andhard, knotlike growthsunder the skinTreatment includespotassium iodideoramphotericin B.1.3BlastomycosisBlastomycosisis caused by the fungusBlastomyces dermatitidis.Infection may spread from thelungsor throughskin woundsProducespus-filled lesionsandmultiple abscessesCan becomesystemic, affecting other organsSevere cases are treated withamphotericin B.1.4Candidiasis (Yeast Infection)Candidiasisis caused by the yeastCandida albicans, which is normally part of the body’snormalflora.Vaginal Yeast InfectionOccurs when the normal balance of microbes is disruptedOften follows destruction oflactobacilliSymptoms include:oDiscomfortoPruritus (itching)oPossible dischargeTreatment includes antifungal drugs such asmiconazole,ketoconazole, anditraconazole.Other FormsThrushwhite patches and inflammation in the mouth and on the tongueOnychosisskin infection seen in people whose hands are frequently exposed to water

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Study GuideSwimmer’s ItchSwimmer’s itchis caused by skin invasion of flatworm larvae fromSchistosomaspecies.The worms themselves arenot pathogenicThey trigger anallergic reactionResults initching and skin irritationInfection occurs while swimming incontaminated water1.5Dracunculiasis (Guinea Worm Disease)Dracunculiasisis caused by the roundwormDracunculus medinensis.Worms live withinskin lesionsThey eventuallyemerge through the skinCommon intropical regionsTreatment involvescareful removal of the wormthrough openings in the lesionKey TakeawayFungal and parasitic skin diseases range from mild, treatable infections to more serious conditions.Early recognition, proper hygiene, and appropriate treatment are essential to prevent spread andcomplications.2.Eye DiseasesThe eyes are delicate organs and can be affected bybacteria, viruses, and parasites. Eyeinfections often causeredness, itching, discharge, pain, or vision problems. Early treatment isimportant because some eye diseases can lead topermanent damage or blindnessif not managedproperly.2.1Conjunctivitis (Pinkeye)Conjunctivitisis an infection of theconjunctiva, the thin membrane that covers the inner eyelid andthe white part of the eye.

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Study GuideBacterial conjunctivitisis commonly calledpinkeyeA frequent cause is the Gram-negative bacteriumHaemophilus aegyptiusSymptoms include:oRed eyesoItchingoDischarge (exudate)It ishighly contagiousSpread occurs throughdroplets and direct contactTreatment usually involvesantibiotic eye ointments or drops, often containingneomycin.2.2TrachomaTrachomais a chronic bacterial eye infection caused byChlamydia trachomatis.The organism is extremely smallIt infects thecorneaCauses rough,sandy or pebble-like growthsThese growths interfere with vision and can lead to blindnessTransmission usually occurs throughdirect contactTreatment includestetracyclineand other antibiotics.2.3Secondary Eye Infections in NewbornsSomesexually transmitted infections (STIs)can cause eye infections in newborns duringchildbirth.Gonococcal OphthalmiaCaused byNeisseria gonorrhoeaeCan lead to severecorneal inflammationMay result inblindnessif untreated
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